(9ci)-2-甲基-1H-吲哚-6-胺合成路线 (共 8 条)
反应条件
1: in toluene
Reflux;
2: With lithium aluminium tetrahydride in tetrahydrofuran
T=0°C; Inert atmosphereReflux;
3: With sodium hydroxide in water
参考文献
Vertex Pharmaceuticals Incorporated
Patent: US2012/309758 A1, 2012 ;
Location in patent: Page/Page column 67 ;
US 20120309758 A1
反应条件
NaOH; LiAlH4 in tetrahydrofuran; water
参考文献
Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;
反应条件
ethanol; nickel; hydrazine hydrate
参考文献
Terent'ew et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 2541,2550; engl. Ausg. S. 2504, 2511
反应条件
1: alcohol; sodium ethylate
2: tin dichloride; hydrochloric acid; alcohol
3: concentrated hydrochloric acid / 130 °C
View Scheme
参考文献
Reissert; Heller
Chemische Berichte, 1904 , vol. 37, p. 4369
反应条件
1: tin dichloride; hydrochloric acid; alcohol
2: concentrated hydrochloric acid / 130 °C
View Scheme
参考文献
Reissert; Heller
Chemische Berichte, 1904 , vol. 37, p. 4369
反应条件
1: alcohol; sodium ethylate
2: tin dichloride; hydrochloric acid; alcohol
3: concentrated hydrochloric acid / 130 °C
View Scheme
参考文献
Reissert; Heller
Chemische Berichte, 1904 , vol. 37, p. 4369
参考文献
Reissert; Heller
Chemische Berichte, 1904 , vol. 37, p. 4369
参考文献
Reissert; Heller
Chemische Berichte, 1904 , vol. 37, p. 4369