4,6-二甲基-1H-苯并[d]咪唑-2(3h)-酮合成路线 （共 4 条）
反应条件
1: 5-nitro-4-amino-1,3-dimethylbenzene With hydrogen; palladium 10 on activated carbon in ethanol P=760.051 Torr; 3 h; 2: bis(trichloromethyl) carbonate in acetonitrile 1 h;
参考文献
MERCK and CO., INC.
Patent: WO2008/130512 A1, 2008 ;
Location in patent: Page/Page column 61-62 ;
WO 2008/130512 A1
反应条件
1: With copper(l) iodide; ammonia; L-proline; sodium hydroxide in water; dimethyl sulfoxide T=20°C; Inert atmosphere; 2: in water; dimethyl sulfoxide T=130°C; Inert atmosphere;
参考文献
Diao, Xiaoqiong; Wang, Yuji; Jiang, Yongwen; Ma, Dawei
Journal of Organic Chemistry, 2009 , vol. 74, # 20 p. 7974 - 7977
反应条件
in acetonitrile 1 h;
参考文献
MERCK and CO., INC.
Patent: WO2006/31610 A2, 2006 ;
Location in patent: Page/Page column 59 ;
WO 2006/031610 A2
参考文献
Clark; Pessolano
Journal of the American Chemical Society, 1958 , vol. 80, p. 1662
