methanol; sodium methylate 5 h; Ambient temperature;

1: 65 percent / K2CO3 / acetone / Ambient temperature 2: 92 percent / NaOMe, MeOH / 5 h / Ambient temperature View Scheme

1: 65 percent / K2CO3 / acetone / Ambient temperature 2: 92 percent / NaOMe, MeOH / 5 h / Ambient temperature View Scheme

β-glycosidase I (92-95 kDa, from Aspergillus oryzae) in acetate buffer T=40°C; pH=4.7; 0.166667 h; Enzyme kinetics; Further Variations:Reagents;

1: 1.) dibutyltin oxide / 1.) MeOH, reflux, 2 h, 2.) CH2Cl2, 0 deg C, 30 min 2: 91 percent / pyridine / CH2Cl2 / 5 h / 0 °C 3: 90 percent / thiourea / methanol / 2 h / Heating 4: 80 percent / 4A molecular sieves, N-iodosuccinimide, silver triflate / CH2Cl2; toluene / 0.17 h / 0 °C 5: 83 percent / NaOMe, MeOH / CH2Cl2 / 5 h / Ambient temperature View Scheme

1: 1.) dibutyltin oxide / 1.) benzene, toluene, reflux, overnight, 2.) benzene, toluene, RT, 2 d 2: pyridine View Scheme

1: 1.) dibutyltin oxide / 1.) benzene, toluene, reflux, overnight, 2.) benzene, toluene, RT, 2 d 2: pyridine 3: 96 percent / AcOH / H2O; diethyl ether / 3 h / Ambient temperature 4: 1.) 3A molecular sieves, 2.) BF3*Et2O / 1.) CH2Cl2, from -25 deg C to -20 deg C, 15 min, 2.) CH2Cl2, 30 min View Scheme

1: 1.) dibutyltin oxide / 1.) benzene, toluene, reflux, overnight, 2.) benzene, toluene, RT, 2 d 2: pyridine 3: 96 percent / AcOH / H2O; diethyl ether / 3 h / Ambient temperature View Scheme