4-乙基氨基-1-(苯基甲基)哌啶-4-甲腈合成路线 （共 5 条）
反应条件
1: With monoethylamine hydrochloride in ethanol; dichloromethane; water; isopropyl alcohol T=0 - 10°C; 2: With potassium cyanide in ethanol; water T=10 - 20°C; 18 h;
参考文献
US2004/214837 A1, ;
Page 26-27 ;
US 20040214837 A1
反应条件
in ethanol; water T=10 - 20°C;
参考文献
Journal of Medicinal Chemistry, , vol. 52, # 2 p. 234 - 237
反应条件
in ethanol; water T=0 - 20°C;
参考文献
WO2007/46550 A1, ;
Page/Page column 127 ;
WO 2007/046550 A1
反应条件
in ethanol; water T=10 - 20°C; 18 h;
参考文献
WO2004/37823 A1, ;
Page 70-71 ;
WO 2004/037823 A1
反应条件
1: With sulfuric acid in dichloromethane T=0 - 20°C; 0.333333 h; 2: With ammonia in water T=0°C; 1 h;
参考文献
TANABE SEIYAKU CO., LTD.
Patent: WO2007/46550 A1, 2007 ;
Location in patent: Page/Page column 127-128 ;
WO 2007/046550 A1
