N-(2,4-二甲氧基苄基)-n-甲胺合成路线 （共 4 条）
反应条件
1: in methanol T=20°C; 1 h; 2: With sodium tetrahydroborate in methanol T=0 - 2°C; 3 h; 3: With hydrogenchloride; water; sodium hydrogencarbonate more than 3 stages;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2008/108380 A2, 2008 ;
Location in patent: Page/Page column 103-104 ;
反应条件
1: With lithium aluminium tetrahydride in diethyl ether T=-78 - 20°C; 2: With sodium hydroxide in diethyl ether; water
参考文献
US2009/23740 A1, ;
Page/Page column 44 ;
反应条件
1: magnesium sulfate / ethanol / 4 h / 78 °C 2: sodium tetrahydroborate / ethanol / 20 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 37 p. 7610 - 7617
反应条件
Ambient temperature; Product distribution;
参考文献
Earle, Martyn J.; Fairhurst, Robin A.; Heaney, Harry; Papageorgiou, George; Wilkins, Robert F.
Tetrahedron Letters, 1990 , vol. 31, # 29 p. 4229 - 4232
