3-甲基-2-苯基-1H-吲哚合成路线 （共 60 条）
反应条件
1: 94 percent / PPh3; t-BuOK / heptane; benzene / 10 - 20 °C
2: 94 percent / SnCl2*2H2O / ethanol / 8 h / 100 °C
3: 96 percent / K3PO4*H2O; Pd(OAc)2; S-Phos / toluene / 2 h / 100 °C
View Scheme
参考文献
Fang, Yuan-Qing; Lautens, Mark
Organic Letters, 2005 , vol. 7, # 16 p. 3549 - 3552
反应条件
1: 79 percent / triethylamine / toluene / 1) reflux, 3 h, 2) room temperature, 16 h
2: 20 percent / n-butyllithium / tetrahydrofuran / 48 h / Ambient temperature
View Scheme
参考文献
Houlihan, William J.; Parrino, Vincent A.; Uike, Yasuyuki
Journal of Organic Chemistry, 1981 , vol. 46, # 22 p. 4511 - 4515
反应条件
[{(η5-C5Me5)IrCl}2(μ-Cl)2]; methanesulfonic acid
T=170°C; 48 h; Inert atmosphere;
参考文献
Tursky, Matyas; Lorentz-Petersen, Linda L. R.; Olsen, Lasse B.; Madsen, Robert
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 24 p. 5576 - 5582
反应条件
Ti(biphenyl)2 in tetrahydrofuran; water
1.25 h; Heating;
参考文献
Fuerstner, Alois; Hupperts, Achim; Ptock, Arne; Janssen, Edo
Journal of Organic Chemistry, 1994 , vol. 59, # 18 p. 5215 - 5229
反应条件
aniline hydrochloric acid
参考文献
Julian et al.
Journal of the American Chemical Society, 1945 , vol. 67, p. 1203,1208
反应条件
1: [Ru2(p-PriC6H4Me)2(μ-Cl)Cl]2; tricyclo[3.3.1.13,7 ]-decane-1-carboxylic acid; potassium carbonate / m-xylene / 22 h / 120 °C / Inert atmosphere
2: sodium ethanolate / dimethyl sulfoxide / 24 h / 20 - 100 °C / Inert atmosphere
View Scheme
参考文献
Ackermann, Lutz; Lygin, Alexander V.
Organic Letters, 2011 , vol. 13, # 13 p. 3332 - 3335
反应条件
1: 79 percent / triethylamine / toluene / 1) reflux, 3 h, 2) room temperature, 16 h
2: 20 percent / n-butyllithium / tetrahydrofuran / 48 h / Ambient temperature
View Scheme
参考文献
Houlihan, William J.; Parrino, Vincent A.; Uike, Yasuyuki
Journal of Organic Chemistry, 1981 , vol. 46, # 22 p. 4511 - 4515
反应条件
T=900°C; P=0.01 Torr; flash vacuum pyrolysis;
参考文献
Randles, K. R.; Storr, R. C.
Tetrahedron Letters, 1987 , vol. 28, # 45 p. 5555 - 5558
反应条件
1: 97 percent / pyridine / CH2Cl2 / Ambient temperature
2: 75 percent / Ti-graphite / tetrahydrofuran / Heating
View Scheme
参考文献
Fuerstner, Alois; Jumbam, Denis N.
Tetrahedron, 1992 , vol. 48, # 29 p. 5991 - 6010
反应条件
hydrogenchloride in ethanol
2.5 h; Ambient temperature; Yield given;
参考文献
Berti, Corrado; Greci, Lucedio; Poloni, Marino; Andreetti, Giovanni Dario; Bocelli, Gabriele; Sgarabotto, Paolo
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 339 - 346
