(-)-(1S,4r)-4-氨基环戊烯-2-羧酸合成路线 （共 15 条）
反应条件
lipase B from Candida antarctica in water; isopropyl alcohol T=60°C; 4 h; Enzymatic reaction; stereospecific reaction;
参考文献
Kiss, Lorand; Forro, Enikoe; Sillanpaeae, Reijo; Fueloep, Ferenc
Synthesis, 2010 , # 1 art. no. T13309SS, p. 153 - 160
反应条件
T=22°C; 16 h; ENZA-25 cells;
参考文献
Nakano, Hiroto; Iwasa, Kazuto; Okuyama, Yuko; Hongo, Hiroshi
Tetrahedron Asymmetry, 1996 , vol. 7, # 8 p. 2381 - 2386
反应条件
hydrogenchloride 72 h; Ambient temperature;
参考文献
Qiu, Jian; Pingsterhaus, Joyce M.; Silverman, Richard B.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4725 - 4728
反应条件
1: 43 percent / various solvent(s) / 0.5 h / Ambient temperature; immobilized lipase PS on diatomite 2: 90 percent / H2O / diisopropyl ether / 3 h / Ambient temperature; lipase PS 3: aq. HCl / 2 h / Heating View Scheme
参考文献
Nakano, Hiroto; Iwasa, Kazuto; Okuyama, Yuko; Hongo, Hiroshi
Tetrahedron Asymmetry, 1996 , vol. 7, # 8 p. 2381 - 2386
反应条件
1: 41 percent / H2O / diisopropyl ether / 3 h / Ambient temperature; lipase PS 2: aq. HCl / 2 h / Heating View Scheme
参考文献
Nakano, Hiroto; Iwasa, Kazuto; Okuyama, Yuko; Hongo, Hiroshi
Tetrahedron Asymmetry, 1996 , vol. 7, # 8 p. 2381 - 2386
反应条件
1: 90 percent / H2O / diisopropyl ether / 3 h / Ambient temperature; lipase PS 2: aq. HCl / 2 h / Heating View Scheme
参考文献
Nakano, Hiroto; Iwasa, Kazuto; Okuyama, Yuko; Hongo, Hiroshi
Tetrahedron Asymmetry, 1996 , vol. 7, # 8 p. 2381 - 2386
反应条件
1: 86 percent / H2O / toluene / 35 °C / pH 7, pig liver esterase (PLE) 2: 6 N aq. HCl / 4 h / Heating View Scheme
参考文献
Mekrami; Sicsic
Tetrahedron Asymmetry, 1992 , vol. 3, # 3 p. 431 - 436
反应条件
hydrogenchloride 4 h; Heating;
参考文献
Mekrami; Sicsic
Tetrahedron Asymmetry, 1992 , vol. 3, # 3 p. 431 - 436
反应条件
hydrogenchloride 2 h; Heating;
参考文献
Nakano, Hiroto; Iwasa, Kazuto; Okuyama, Yuko; Hongo, Hiroshi
Tetrahedron Asymmetry, 1996 , vol. 7, # 8 p. 2381 - 2386
反应条件
1: 0.5 h / 200 °C 2: H2NNH2 / methanol / 0.5 h / Heating 3: 90 percent / hydrogen / 10percentPd-C / acetic acid / Ambient temperature View Scheme
参考文献
Allan; Fong
Australian Journal of Chemistry, 1986 , vol. 39, # 6 p. 855 - 864
