(-)-(1S,4r)-4-氨基环戊烯-2-羧酸合成路线 (共 15 条)
反应条件
hydrogenchloride in various solvent(s) 24 h; Ambient temperature; Yield given;
参考文献
Tetrahedron Asymmetry, , vol. 7, # 8 p. 2381 - 2386
反应条件
sodium hydroxide in methanol Ambient temperature;
参考文献
Qiu, Jian; Pingsterhaus, Joyce M.; Silverman, Richard B.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4725 - 4728
反应条件
1: Et3N / methanol / 3 h / 20 °C
2: CH2Cl2 / 1 h
View Scheme
参考文献
Qiu, Jian; Pingsterhaus, Joyce M.; Silverman, Richard B.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4725 - 4728
反应条件
1: 18 h / Heating
2: pyridine / 1 h / Ambient temperature
View Scheme
参考文献
Csuk, Rene; Doerr, Petra
Tetrahedron: Asymmetry, 1994 , vol. 5, # 2 p. 269 - 276
反应条件
1: 18 h / Heating
2: pyridine / 1 h / Ambient temperature
View Scheme
参考文献
Csuk, Rene; Doerr, Petra
Tetrahedron: Asymmetry, 1994 , vol. 5, # 2 p. 269 - 276