3-(1-三苯甲游基咪唑-4-基)丙酸甲酯合成路线 (共 13 条)
反应条件
triethylamine in N,N-dimethyl-formamide 2 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 2 p. 725 - 736
反应条件
triethylamine in acetonitrile 12 h; Ambient temperature;
参考文献
Journal of medicinal chemistry, , vol. 39, # 6 p. 1220 - 1226
反应条件
hydrogen; palladium on activated charcoal in methanol 4 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 13, # 23 p. 6309 - 6323
反应条件
1: 75 percent / triethylamine / tetrahydrofuran / 16 h / 20 °C 2: 99 percent / H2 / Pd/C / methanol / 4 h View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 13, # 23 p. 6309 - 6323
反应条件
1: 75 percent / triethylamine / tetrahydrofuran / 16 h / 20 °C 2: 99 percent / H2 / Pd/C / methanol / 4 h View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 13, # 23 p. 6309 - 6323
反应条件
1: 100 percent / HCl / 5 h / Heating 2: 75 percent / triethylamine / tetrahydrofuran / 16 h / 20 °C 3: 99 percent / H2 / Pd/C / methanol / 4 h View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 13, # 23 p. 6309 - 6323
反应条件
1: 70 percent / Et3N / dimethylformamide / 3 h / Ambient temperature 2: 59 percent / H2 / 10percent Pd/C / CH2Cl2; ethanol / 5 h / Ambient temperature View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 5, # 10 p. 1989 - 1998
反应条件
1: sulfuric acid; sodium sulfate / 24 h / Reflux 2: palladium 10 on activated carbon; hydrogen / methanol / 8 h / 20 °C 3: triethylamine / dichloromethane / 2 h / 20 °C View Scheme
参考文献
Amino Acids, , vol. 40, # 2 p. 411 - 420
反应条件
1: palladium 10 on activated carbon; hydrogen / methanol / 8 h / 20 °C 2: triethylamine / dichloromethane / 2 h / 20 °C View Scheme
参考文献
Amino Acids, , vol. 40, # 2 p. 411 - 420
反应条件
1: 7.87 g / HCl / 2 h / Heating 2: 15.9 g / Et3N / dimethylformamide / 72 h / 20 °C View Scheme
参考文献
Helvetica Chimica Acta, , vol. 87, # 12 p. 3131 - 3159