4-氨基-7H-吡咯并[2,3-d]嘧啶-2-磺酸合成路线 （共 2 条）
反应条件
potassium hydroxide; dihydrogen peroxide T=5 - 15°C;
参考文献
Bio, Matthew M.; Xu, Feng; Waters, Marjorie; Williams, J. Michael; Savary, Kimberly A.; Cowden, Cameron J.; Yang, Chunhua; Buck, Elizabeth; Song, Zhiguo J.; Tschaen, David M.; Volante; Reamer, Robert A.; Grabowski, Edward J. J.
Journal of Organic Chemistry, 2004 , vol. 69, # 19 p. 6257 - 6266
反应条件
1: 84 percent / sulfuric acid / 5.5 h / 20 - 75 °C 2: 85.6 percent / N,N-dimethylacetamide; N,N-diisopropylethylamine View Scheme
参考文献
Bio, Matthew M.; Xu, Feng; Waters, Marjorie; Williams, J. Michael; Savary, Kimberly A.; Cowden, Cameron J.; Yang, Chunhua; Buck, Elizabeth; Song, Zhiguo J.; Tschaen, David M.; Volante; Reamer, Robert A.; Grabowski, Edward J. J.
Journal of Organic Chemistry, 2004 , vol. 69, # 19 p. 6257 - 6266
