2,2-二甲基-3-丁烯酸合成路线 （共 52 条）
反应条件
gas phase pyrolysis; Kinetics;
参考文献
al-Borno, Amal; Bigley, David B.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , # 9 p. 1311 - 1312
参考文献
Arnold et al.
Journal of the American Chemical Society, 1950 , vol. 72, p. 4359
反应条件
2: Irradiation View Scheme
参考文献
Schexnayder,M.A.; Engel,P.S.
Journal of the American Chemical Society, 1975 , vol. 97, p. 4825 - 4836
反应条件
sulfuric acid; water
参考文献
Blaise; Courtot
Bulletin de la Societe Chimique de France, 1906 , vol. <3> 35, p. 591,597
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1905 , vol. 141, p. 725
参考文献
Blaise; Courtot
Bulletin de la Societe Chimique de France, 1906 , vol. <3> 35, p. 591,597
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1905 , vol. 141, p. 725
反应条件
hydrogenchloride; n-butyllithium in tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide
参考文献
Palladino, Michael A.; Lloyd, George Kenneth; Hayashi, Yoshio; Nicholson, Benjamin
Patent: US2005/197344 A1, 2005 ;
反应条件
1: thionyl chloride; DMF / 20 - 80 °C
2: 8.1 g / n-BuLi / tetrahydrofuran; hexane / 1 h / -65 °C
View Scheme
参考文献
NEREUS PHARMACEUTICALS, INC.; YAMAZAKI, Yuri; HAYASHI, Yoshio
Patent: WO2011/84962 A1, 2011 ;
反应条件
lithium aluminium tetrahydride in diethyl ether
T=0 - 25°C; Inert atmosphere;
参考文献
Gu, Zhenhua; Zakarian, Armen
Organic Letters, 2011 , vol. 13, # 5 p. 1080 - 1082
反应条件
(NH4)2S2O8; silver nitrate
参考文献
Jacobsen,N.; Torssell,K.
Acta Chemica Scandinavica (1947-1973), 1973 , vol. 27, # 9 p. 3211 - 3216
反应条件
oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane
T=0 - 20°C; 17 h;
参考文献
NEREUS PHARMACEUTICALS, INC.; YAMAZAKI, Yuri; HAYASHI, Yoshio
Patent: WO2011/84962 A1, 2011 ;
Location in patent: Page/Page column 29; 33 ;
