3-(溴甲基)-2H-吡唑并[3,4-b]吡啶合成路线 （共 4 条）
反应条件
N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane Reflux;
参考文献
SU, Wei-Guo; JIA, Hong; DAI, Guangxiu
Patent: US2012/245178 A1, 2012 ;
Location in patent: Page/Page column 13 ;
US 20120245178 A1
反应条件
1: hydrazine; pyridine / Reflux 2: 4-(N,N-dimethlyamino)pyridine; triethylamine / ethyl acetate / 20 °C 3: 2,2'-azo-bisisobutyronitrile; N-bromosuccinmide / tetrachloromethane / Reflux View Scheme
参考文献
SU, Wei-Guo; JIA, Hong; DAI, Guangxiu
Patent: US2012/245178 A1, 2012 ;
US 20120245178 A1
反应条件
1: 4-(N,N-dimethlyamino)pyridine; triethylamine / ethyl acetate / 20 °C 2: 2,2'-azo-bisisobutyronitrile; N-bromosuccinmide / tetrachloromethane / Reflux View Scheme
参考文献
SU, Wei-Guo; JIA, Hong; DAI, Guangxiu
Patent: US2012/245178 A1, 2012 ;
US 20120245178 A1
反应条件
1: diethyl ether; tetrahydrofuran / 0 - 20 °C 2: hydrazine; pyridine / Reflux 3: 4-(N,N-dimethlyamino)pyridine; triethylamine / ethyl acetate / 20 °C 4: 2,2'-azo-bisisobutyronitrile; N-bromosuccinmide / tetrachloromethane / Reflux View Scheme
参考文献
SU, Wei-Guo; JIA, Hong; DAI, Guangxiu
Patent: US2012/245178 A1, 2012 ;
US 20120245178 A1
