N-丙-2-烯基苯甲酰胺合成路线 （共 65 条）
反应条件
tert.-butylhydroperoxide; 5,10,15,20-tetrakisphenylporphyrinatoiron(III) chloride in dichloromethane
T=30°C; Title compound not separated from byproducts;
参考文献
Constantino, Luis; Iley, Jim
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 13 p. 1894 - 1900
反应条件
1.1: triethylamine / CH2Cl2 / 0 °C
2.1: NaI / acetone / Heating
3.1: NaH / dimethylformamide / Heating
4.1: O-mesitylenesulfonylhydroxylamine / CH2Cl2 / 0.5 h / 20 °C
4.2: 78 percent / potassium carbonate / CH2Cl2 / 12 h / 20 °C
View Scheme
参考文献
Matsuo, Jun-Ichi; Kozai, Takaaki; Ishibashi, Hiroyuki
Organic Letters, 2006 , vol. 8, # 26 p. 6095 - 6098
反应条件
1.1: NaH / dimethylformamide / Heating
2.1: O-mesitylenesulfonylhydroxylamine / CH2Cl2 / 0.5 h / 20 °C
2.2: 78 percent / potassium carbonate / CH2Cl2 / 12 h / 20 °C
View Scheme
参考文献
Matsuo, Jun-Ichi; Kozai, Takaaki; Ishibashi, Hiroyuki
Organic Letters, 2006 , vol. 8, # 26 p. 6095 - 6098
反应条件
1.1: triethylamine / CH2Cl2 / 0 °C
2.1: triethylamine / CH2Cl2 / 0 °C
3.1: NaI / acetone / Heating
4.1: NaH / dimethylformamide / Heating
5.1: O-mesitylenesulfonylhydroxylamine / CH2Cl2 / 0.5 h / 20 °C
5.2: 78 percent / potassium carbonate / CH2Cl2 / 12 h / 20 °C
View Scheme
参考文献
Matsuo, Jun-Ichi; Kozai, Takaaki; Ishibashi, Hiroyuki
Organic Letters, 2006 , vol. 8, # 26 p. 6095 - 6098
反应条件
1: CCl4 / Heating
2: 1 M aq. HCl / tetrahydrofuran / Ambient temperature
View Scheme
参考文献
DeBruin, Kenneth E.; Boros, Eric E.
Journal of Organic Chemistry, 1990 , vol. 55, # 25 p. 6091 - 6098
反应条件
water in tetrahydrofuran; diethyl ether
Ambient temperature;
参考文献
Barluenga, Jose; Foubelo, Francisco; Fananas, Francisco J.; Yus, Miguel
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 553 - 557
反应条件
Iron (III) nitrate nonahydrate
T=125°C; 24 h; Neat (no solvent)Sealed tube;
参考文献
Allen, C. Liana; Lapkin, Alexei A.; Williams, Jonathan M.J.
Tetrahedron Letters, 2009 , vol. 50, # 29 p. 4262 - 4264
参考文献
Carlsen, Per H. J.; Joergensen, Kare B.
Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 4 p. 805 - 808
反应条件
1: 1.) phenyl-lithium, 2.) lithium naphthalenide / 1.) diethyl ether, THF, -78 deg C, 30 min, 2.) -78 deg C, 2 h
2: 91 percent / H2O / diethyl ether; tetrahydrofuran / Ambient temperature; reactions with other electrophiles
View Scheme
参考文献
Barluenga, Jose; Foubelo, Francisco; Fananas, Francisco J.; Yus, Miguel
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 553 - 557
反应条件
1: 1.) phenyl-lithium, 2.) lithium naphthalenide / 1.) diethyl ether, THF, -78 deg C, 30 min, 2.) -78 deg C, 2 h
2: 91 percent / H2O / diethyl ether; tetrahydrofuran / Ambient temperature; reactions with other electrophiles
View Scheme
参考文献
Barluenga, Jose; Foubelo, Francisco; Fananas, Francisco J.; Yus, Miguel
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 553 - 557
