N-丙-2-烯基苯甲酰胺合成路线 （共 65 条）
反应条件
oxygen; cobalt(II) 2,4-pentanedionate in isopropyl alcohol
T=75°C; 1 h;
参考文献
Kato; Yamada; Takai; Inoki; Isayama
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 1 p. 179 - 186
反应条件
O,N-bis-(trifluoroacetyl)-hydroxylamine; hydroxylamine in 1,4-dioxane; water
T=100°C; 0.333333 h;
参考文献
Kleinke, Andrew S.; Jamison, Timothy F.
Organic Letters, 2013 , vol. 15, # 3 p. 710 - 713
反应条件
1: 91 percent / LDA / tetrahydrofuran; hexane / -70 deg C, 10 min, then to 0 deg C
2: 1.) sec-butyllithium / 1.) THF, cyclohexane, -70 deg C, 10 min 2.) THF, to 0 deg C
View Scheme
参考文献
Fisher, Lawrence E.; Muchowski, Joseph M.; Clark, Robin D.
Journal of Organic Chemistry, 1992 , vol. 57, # 9 p. 2700 - 2705
反应条件
1: 85 percent / Lawesson's reagent / tetrahydrofuran / Heating
2: 85 percent / CHCl3 / 3 h
3: 91 percent / Ph3SnH / 1 h
View Scheme
参考文献
Engman, Lars
Journal of Organic Chemistry, 1991 , vol. 56, # 10 p. 3425 - 3430
反应条件
1: 91 percent / LDA / tetrahydrofuran; hexane / -70 deg C, 10 min, then to 0 deg C
2: 1.) sec-butyllithium / 1.) THF, cyclohexane, -70 deg C, 10 min 2.) THF, to 0 deg C
View Scheme
参考文献
Fisher, Lawrence E.; Muchowski, Joseph M.; Clark, Robin D.
Journal of Organic Chemistry, 1992 , vol. 57, # 9 p. 2700 - 2705
反应条件
1.1: thionyl chloride / 6 h / 80 °C
2.1: triethylamine / dichloromethane / 0.17 h / 0 °C
2.2: 2 h / 0 - 50 °C
3.1: [bis(acetoxy)iodo]benzene / acetonitrile / 1 h / 120 °C / |Sealed tube
View Scheme
参考文献
Lin, Jian-Ping; Zhang, Feng-Hua; Long, Ya-Qiu
Organic Letters, 2014 , vol. 16, # 11 p. 2822 - 2825
参考文献
Goodman; Winstein
Journal of the American Chemical Society, 1957 , vol. 79, p. 4788,4791
反应条件
acetic anhydride; periodic acid; chromium(VI) oxide in acetonitrile
T=20°C; 2 h;
参考文献
Xu, Liang; Zhang, Suhong; Trudell, Mark L.
Chemical Communications, 2004 , # 14 p. 1668 - 1669
反应条件
1: 91 percent / LDA / tetrahydrofuran; hexane / -70 deg C, 10 min, then to 0 deg C
2: 1.) sec-butyllithium / 1.) THF, cyclohexane, -70 deg C, 10 min 2.) THF, to 0 deg C
View Scheme
参考文献
Fisher, Lawrence E.; Muchowski, Joseph M.; Clark, Robin D.
Journal of Organic Chemistry, 1992 , vol. 57, # 9 p. 2700 - 2705
反应条件
1: 91 percent / LDA / tetrahydrofuran; hexane / -70 deg C, 10 min, then to 0 deg C
2: 1.) sec-butyllithium / 1.) THF, cyclohexane, -70 deg C, 10 min 2.) THF, to 0 deg C
View Scheme
参考文献
Fisher, Lawrence E.; Muchowski, Joseph M.; Clark, Robin D.
Journal of Organic Chemistry, 1992 , vol. 57, # 9 p. 2700 - 2705
