6-溴-4-氯-1(2H)-酞嗪酮合成路线 (共 2 条)
反应条件
1: With trichlorophosphate 3 h; Heating / reflux; 2: With sodium hydroxide; water in 1,4-dioxane T=50°C; 0.5 h; Product distribution / selectivity;
参考文献
FOREST LABORATORIES HOLDINGS LIMITED
Patent: WO2008/61108 A2, 2008 ;
Location in patent: Page/Page column 78 ;
反应条件
1: With thionyl chloride; trichlorophosphate 4 h; Heating / reflux; 2: With sodium hydroxide; water in 1,4-dioxane T=40°C; 2.5 h; Product distribution / selectivity;
参考文献
FOREST LABORATORIES HOLDINGS LIMITED
Patent: WO2008/61108 A2, 2008 ;
Location in patent: Page/Page column 66 ;