1: 2-(1H-imidazole-2-ylcarbonyl)-(1S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline With titanium(IV) isopropylate in tetrahydrofuran T=20°C; 0.5 h; 2: (3R)-3-hydroxy-1-azabicyclo[2.2.2]octane With sodium hydride in tetrahydrofuran Reflux; Product distribution / selectivity;