anhydrous iron chloride in tetrahydrofuran T=0 - 5°C; 2 h; Inert atmosphere; optical yield given as percent de;

1: (4-Methylphenyl)-magnesium bromide With zinc(II) chloride in tetrahydrofuran T=0 - 5°C; Inert atmosphere; 2: (E)-methyl 3-(p-toluenesulfonyloxy)but-2-enoate With Pd(PPh3)2Cl2 in tetrahydrofuran T=20 - 25°C; Negishi coupling reaction; 1 h; Inert atmosphere;

anhydrous iron chloride in tetrahydrofuran T=0 - 5°C; 2 h; Inert atmosphere; optical yield given as percent de;