1: 84 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 48 h / Ambient temperature 2: 81 percent / hydrogen / 10percent Pd-C / methanol; ethyl acetate / Ambient temperature View Scheme

1: 84 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 48 h / Ambient temperature 2: 81 percent / hydrogen / 10percent Pd-C / methanol; ethyl acetate / Ambient temperature View Scheme

Multi-step reaction with 5 steps 1: p-TsOH / methanol; CH2Cl2 / 12 h / Ambient temperature2: 74 percent / pyridine, Ph3P, CI4 / 12 h / Ambient temperature3: 95percent NaH / dimethylformamide / 20 h4: 1.) aq. HgCl2, 2.) MsCl, DMAP, pyridine / 1.) acetone, 100 deg C, 1.5 h, 2.) r.t., 4 h5: 1.) CeCl3*7H2O, 2.) NaBH4 / 1.) MeOH, -50 deg C, 10 min, 2.) -50 deg C, 5 h