2-甲基-4-苯基-2-丁醇合成路线 （共 84 条）
反应条件
lead(IV) acetate in propionic acid; pentane 5 h; Heating;
参考文献
Liebigs Annalen der Chemie, , # 4 p. 610 - 623
反应条件
zinc in isopropyl alcohol 48 h; Irradiation;
参考文献
Tetrahedron, , vol. 42, # 5 p. 1487 - 1496
反应条件
1: 98 percent / HBF4*Et2O / CH2Cl2 / 1.5 h / Ambient temperature 2: 62 percent / MCPBA, tert-butyl-4-hydroxy-5-methylphenylsulfide / N,N-dimethyl-acetamide / 60 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 4 p. 317 - 338
反应条件
methanol; [Zn4O(CF3CO2)6] 96 h; RefluxInert atmosphere;
参考文献
Iwasaki, Takanori; Agura, Kazushi; Maegawa, Yusuke; Hayashi, Yukiko; Ohshima, Takashi; Mashima, Kazushi
Chemistry - A European Journal, 2010 , vol. 16, # 38 p. 11567 - 11571
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; Sm(OTf)2 1.) THF, cyclohexane, RT, 1 h, 2.) THF, cyclohexane, RT, 0.5 h; Yield given. Multistep reaction;
参考文献
Chemistry Letters, , # 11 p. 1981 - 1984
反应条件
1: 10.7 g / TiCl4 / CH2Cl2 / 6 h / Ambient temperature 2: p-TsOH / benzene / 5.25 h / Heating 3: 57 percent / 1.) -23 deg C, 5.25 h, 2.) room temperature, 45 min 4: 90 percent / Raney nickel / ethanol / 20 h / 90 °C 5: 98 percent / HBF4*Et2O / CH2Cl2 / 1.5 h / Ambient temperature 6: 62 percent / MCPBA, tert-butyl-4-hydroxy-5-methylphenylsulfide / N,N-dimethyl-acetamide / 60 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 4 p. 317 - 338
反应条件
1: p-TsOH / benzene / 5.25 h / Heating 2: 57 percent / 1.) -23 deg C, 5.25 h, 2.) room temperature, 45 min 3: 90 percent / Raney nickel / ethanol / 20 h / 90 °C 4: 98 percent / HBF4*Et2O / CH2Cl2 / 1.5 h / Ambient temperature 5: 62 percent / MCPBA, tert-butyl-4-hydroxy-5-methylphenylsulfide / N,N-dimethyl-acetamide / 60 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 4 p. 317 - 338
反应条件
1: 90 percent / Raney nickel / ethanol / 20 h / 90 °C 2: 98 percent / HBF4*Et2O / CH2Cl2 / 1.5 h / Ambient temperature 3: 62 percent / MCPBA, tert-butyl-4-hydroxy-5-methylphenylsulfide / N,N-dimethyl-acetamide / 60 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 4 p. 317 - 338
反应条件
(i) (esterification), (ii) /BRN= 1209226/; Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 85, p. 1597 - 1601
反应条件
diethyl ether; magnesium
参考文献
Chemische Berichte, , vol. 37, p. 2313
Chemische Berichte, , vol. 40, p. 1771
