1: 81.5 percent / K2CO3; NaI / acetone / 48 h / Heating 2: 87 percent / H2 / 10 percent Pd/C / ethanol / 20 °C / 760 Torr 3: KOH / ethanol / 20 °C View Scheme
参考文献
Louis, Simon N.; Nero, Tracy L.; Iakovidis, Dimitri; Colagrande, Felicia M.; Jackman, Graham P.; Louis, William J.
European Journal of Medicinal Chemistry, 1999 , vol. 34, # 11 p. 919 - 937
Barbera, Joaquin; Bardaji, Manuel; Jimenez, Josefina; Laguna, Antonio; Martinez, M. Pilar; Oriol, Luis; Serrano, Jose Luis; Zaragozano, Irene
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1.1: triphenylphosphine; di-isopropyl azodicarboxylate / dichloromethane / Inert atmosphere 2.1: hydrogen / palladium 10 on activated carbon / tetrahydrofuran / 16 h / 20 °C 3.1: sodium hydroxide / water / 0.5 h / 40 °C / pH 14 3.2: 24.75 h / 20 - 60 °C View Scheme
参考文献
THE UNIVERSITY OF NOTTINGHAM; MISTRY, Shailesh; DARAS, Etienne; FROMONT, Christophe; JADHAV, Gopal; FISCHER, Peter Martin; KELLAM, Barrie; HILL, Stephen John; BAKER, Jillian Glenda
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