1.1: sodium hydroxide / water / 1 h / 20 °C 1.2: polyethylene glycol / 15 h / 110 °C 2.1: hydrogenchloride / water / 1 h / |Cooling with ice View Scheme
pyridine; phenylphosphoric acid dichloride in dichloromethane T=-15°C; 3 h; variation of reagents, temperature and reaction time; Product distribution;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 30, # 5 p. 1646 - 1652