1: 2-(phenyl)ethyl bromide With magnesium in tetrahydrofuran
Inert atmosphereReflux;
2: (S)-4-i-propyl-5,5-dimethyl-3-[(RP)-methyl(phenyl)phosphinoyll]oxazolidin-2-one in tetrahydrofuran
T=0°C; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Adams, Harry; Collins, Rebecca C.; Jones, Simon; Warner, Christopher J. A.
Organic Letters, 2011 , vol. 13, # 24 p. 6576 - 6579