1-(2-羟乙基)哌嗪合成路线 （共 140 条）
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 2 h;
参考文献
WO2012/48259 A2, ;
Page/Page column 41 ;
WO 2012/048259 A2
反应条件
diethylamine; Pd(0) (in situ from Pd(OAc)2 and m.sulfonated triphenylphosphine) in water; acetonitrile 0.25 h; 5 molpercent catalyst;
参考文献
Tetrahedron Letters, , vol. 35, # 47 p. 8783 - 8786
反应条件
2-mercapto benzoic acid; 1,4-di(diphenylphosphino)-butane; bis(dibenzylideneacetone)-palladium(0) in tetrahydrofuran T=20°C; 0.5 h;
参考文献
Tetrahedron Letters, , vol. 36, # 8 p. 1267 - 1270
反应条件
ammonia; hydrogen; Ni/Re (6.8wtpercent/1.8wtpercent) on silica/alumina (80/20) T=165°C; P=85781.4 - 99537.9 Torr; 4 h; Autoclave; Product distribution / selectivity;
参考文献
WO2010/42159 A1, ;
Page/Page column 30-31 ;
反应条件
ammonia; hydrogen; Ni/Re (6.8wtpercent/1.8wtpercent) on silica/alumina (80/20) T=170°C; P=85781.4 - 99537.9 Torr; 16 h; Autoclave; Product distribution / selectivity;
参考文献
WO2010/42159 A1, ;
Page/Page column 30-31 ;
反应条件
ammonia; hydrogen; Ni/Re (6.8wtpercent/1.8wtpercent) on silica/alumina (80/20) T=170°C; P=85781.4 - 99537.9 Torr; 10 h; Autoclave; Product distribution / selectivity;
参考文献
WO2010/42159 A1, ;
Page/Page column 30-31 ;
反应条件
in various solvent(s) T=40°C; 0.5 h;
参考文献
J. Appl. Chem. USSR (Engl. Transl.), , vol. 53, # 1 p. 199 - 203,174 - 178
反应条件
[{(η5-C5Me5)IrCl}2(μ-Cl)2]; sodium hydrogencarbonate in water T=140°C; 96 h; Inert atmosphereHeating;
参考文献
European Journal of Organic Chemistry, , # 34 p. 6752 - 6759
