in methanol; N,N-dimethyl-formamide T=70°C; 1 h; Further byproducts given;

adenosine deaminase in water; dimethyl sulfoxide 72 h; Ambient temperature0.1M sodium phosphate buffer;

copper acetylacetonate in N,N-dimethyl-formamide T=70°C; 1 h; Further byproducts given;

1: 2,6-Diamino-9-(β-D-ribofuranosyl)-purine With tin(ll) chloride in N,N-dimethyl-formamide T=50°C; 0.25 h; 2: diazomethane in N,N-dimethyl-formamide T=50°C; 3: With calf spleen adenosine deaminase; sodium salt of phosphorous acid in dimethyl sulfoxide T=20°C; pH=7.4; 36 h;

1: 1.) hexamethyldisilazane, chlorotrimethylsilane; 2.) hexamethyldisilazane, CF3SO3SiMe3, NH3 / 1.) reflux, 16 h; 2.) 150 deg C, 3 d (sealed bomb) 2: 47 percent / SnCl2*2H2O / dimethylformamide; 1,2-dimethoxy-ethane / 50 °C 3: 92 percent / adenosine deaminase / dimethylsulfoxide; H2O / 72 h / Ambient temperature; 0.1M sodium phosphate buffer View Scheme

1: 47 percent / SnCl2*2H2O / dimethylformamide; 1,2-dimethoxy-ethane / 50 °C 2: 92 percent / adenosine deaminase / dimethylsulfoxide; H2O / 72 h / Ambient temperature; 0.1M sodium phosphate buffer View Scheme

in methanol; N,N-dimethyl-formamide T=70°C; 1 h; Further byproducts given. Title compound not separated from byproducts;

in methanol; N,N-dimethyl-formamide T=70°C; 1 h; Further byproducts given. Title compound not separated from byproducts;

pyridine; 4,4'-diaminostilbene-2,2'-disulfonic acid; trifluoroacetic acid 1.) CH2Cl2, r.t., 2.) CH2Cl2; Yield given. Multistep reaction. Yields of byproduct given;

copper acetylacetonate in N,N-dimethyl-formamide T=70°C; 1 h; without metallo-organic compound; Product distribution;