(S)-2-甲基丁酸甲酯合成路线 （共 17 条）
反应条件
in diethyl ether T=20°C; Esterification; 1 h;
参考文献
Tashiro, Takuya; Mori, Kenji
European Journal of Organic Chemistry, 1999 , # 9 p. 2167 - 2173
反应条件
1: (E)-2-methyl-2-butenoic acid With hydrogen; 2,2'-bis(diphenylphosphino)-1,1'-binaphthyl ruthenium dichloride in methanol T=50°C; Catalytic hydrogenation; P=30002.4 Torr; 2: methanol With thionyl chloride Esterification; 2 h; Title compound not separated from byproducts;
参考文献
Ter Halle, Rob; Schulz, Emmanuelle; Spagnol, Michel; Lemaire, Marc
Tetrahedron Letters, 2000 , vol. 41, # 18 p. 3323 - 3326
反应条件
1: 85 percent / CrO3 / acetone / 2 h / 20 °C 2: 76 percent / diethyl ether / 1 h / 20 °C View Scheme
参考文献
Freudenberg; Lwowski
Justus Liebigs Annalen der Chemie, 1955 , vol. 594, p. 76,85
反应条件
1: 4-(N,N-dimethlyamino)pyridine; diisopropyl-carbodiimide / dichloromethane / 12 h / 20 °C 2: QT / toluene / 72 h / 20 °C 3: lithium hydroxide hydrate / tetrahydrofuran; water / 3 h / 20 °C 4: diethyl ether / 0.5 h / 20 °C 5: sodium hypophosphite monohydrate / tetrahydrofuran; methanol / aq. acetate buffer View Scheme
参考文献
Rana, Nirmal K.; Singh, Vinod K.
Organic Letters, 2011 , vol. 13, # 24 p. 6520 - 6523
反应条件
1: batatoside IV With water; potassium hydroxide T=90°C; 2 h; 2: methanol With sulfuric acid in water
参考文献
Yin, Yong-Qin; Huang, Xue-Feng; Kong, Ling-Yi; Niwa, Masatake
Chemical and Pharmaceutical Bulletin, 2008 , vol. 56, # 12 p. 1670 - 1674
反应条件
1: batatoside A With potassium hydroxide T=90°C; 2 h; Reflux; 2: methanol With sulfuric acid in water
参考文献
Yin, Yongqin; Li, Yi; Kong, Lingyi
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 7 p. 2363 - 2368
反应条件
1: batatoside C With potassium hydroxide T=90°C; 2 h; Reflux; 2: methanol With sulfuric acid in water
参考文献
Yin, Yongqin; Li, Yi; Kong, Lingyi
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 7 p. 2363 - 2368
反应条件
1: batatoside D With potassium hydroxide T=90°C; 2 h; Reflux; 2: methanol With sulfuric acid in water
参考文献
Yin, Yongqin; Li, Yi; Kong, Lingyi
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 7 p. 2363 - 2368
反应条件
1: batatoside F With potassium hydroxide T=90°C; 2 h; Reflux; 2: methanol With sulfuric acid in water
参考文献
Yin, Yongqin; Li, Yi; Kong, Lingyi
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 7 p. 2363 - 2368
反应条件
1: batatoside III With water; potassium hydroxide T=90°C; 2 h; 2: methanol With sulfuric acid in water
参考文献
Yin, Yong-Qin; Huang, Xue-Feng; Kong, Ling-Yi; Niwa, Masatake
Chemical and Pharmaceutical Bulletin, 2008 , vol. 56, # 12 p. 1670 - 1674
