4-(1,3-二氧代异吲哚啉-2-基)丁酰氯合成路线 （共 16 条）
反应条件
hydrogen; Pd-BaSO4 in xylene 6 h; Heatingcatalyst poison; Title compound not separated from byproducts;
参考文献
Vinograd, L. Kh.; Suvorov, N. N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 9 p. 984 - 988
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , vol. 20, # 9 p. 1206 - 1210
反应条件
1: diethyl ether; ammonia 2: thionyl chloride View Scheme
参考文献
King; L'Ecuyer; Openshaw
Journal of the Chemical Society, 1936 , p. 352
反应条件
in diethyl ether; benzene
T=-10 - 0°C; 2 h;
参考文献
Gomza, L. D.; Zalesov, V. V.; Yeikhman, G. A.; Legotkina, G. I.; Andreichikov, Yu. S.
J. Gen. Chem. USSR (Engl. Transl.), 1982 , vol. 52, # 10 p. 2322 - 2328,2065 - 2070
反应条件
Yield given. Multistep reaction;
参考文献
Elz, Sigurd; Schunack, Walter
Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1987 , vol. 42, # 2 p. 238 - 242
反应条件
hydrogen; Pd-BaSO4 in xylene
6 h; Heatingcatalyst poison; Title compound not separated from byproducts;
参考文献
Vinograd, L. Kh.; Suvorov, N. N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 9 p. 984 - 988
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , vol. 20, # 9 p. 1206 - 1210
反应条件
1: palladium 10 on activated carbon; hydrogen; 2,6-dimethylpyridine / tetrahydrofuran / 6 h / 22 °C / 775.74 Torr
2: sodium tris(acetoxy)borohydride / dichloromethane
View Scheme
参考文献
Crawford, Jason B.; Chen, Gang; Gauthier, David; Wilson, Trevor; Carpenter, Bryon; Baird, Ian R.; McEachern, Ernie; Kaller, Alan; Harwig, Curtis; Atsma, Bem; Skerlj, Renato T.; Bridger, Gary J.
Organic Process Research and Development, 2008 , vol. 12, # 5 p. 823 - 830
