反应条件
1: 96 percent / AcOH / tetrahydrofuran; H2O / 24 h / 24 °C
2: 65 percent / MnO2 / CH2Cl2 / 23 h / 24 °C
3: 98 percent / NaOMe / methanol / 1.25 h / 0 °C
4: xylene / 5 h / Heating; variation of time
5: 85 percent / anhydrous HCl / methanol / 12 h / 70 °C
6: 76 percent / tetrahydrofuran / 0.33 h / 22 °C
7: 81 percent / 1.) H2O2, BF3*Et2O / 3.) DMAP / 1.) CH2Cl2; 2.) CH2Cl2, 8 min, 23 deg C; 3.) CH2Cl2, 23 deg C, 18 h
8: 96 percent / LiOH / tetrahydrofuran; methanol; H2O / 1 h / 50 °C
View Scheme
参考文献
Boger,D.L.; Coleman,R.S.
Journal of the American Chemical Society, 1987 , vol. 109, p. 2717
