2-氯-5-硝基嘧啶合成路线

参考文献

Icagen, Inc.
Patent: US2003/181465 A1, 2003 ;
US 20030181465 A1

3264-10-62-羟基-5-硝基嘧啶

10320-42-02-氯-5-硝基嘧啶

参考文献

Hurst, Derek T.
Heterocycles, 1984 , vol. 22, # 1 p. 79 - 84

3073-77-62-氨基-5-硝基嘧啶

10320-42-02-氯-5-硝基嘧啶

参考文献

Amato, George; Roeloffs, Rosemarie; Rigdon, Greg C.; Antonio, Brett; Mersch, Theresa; McNaughton-Smith, Grant; Wickenden, Alan D.; Fritch, Paul; Suto, Mark J.
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 6 p. 481 - 484

10320-42-02-氯-5-硝基嘧啶

56621-90-05-氨基-2-氯嘧啶

参考文献

Pathway Therapeutics Limited
Patent: US2011/9405 A1, 2011 ;
Location in patent: Page/Page column 56 ;

10320-42-02-氯-5-硝基嘧啶+

5188-07-8甲硫醇钠

14001-70-8(8CI,9CI)-2-(甲基硫代)-5-硝基嘧啶

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2009/149139 A1, 2009 ;
Location in patent: Page/Page column 56-57 ;

10320-42-02-氯-5-硝基嘧啶+

124-41-4甲醇钠

14001-69-52-甲氧基-5-硝基嘧啶

参考文献

Pathway Therapeutics Limited
Patent: US2011/9405 A1, 2011 ;
Location in patent: Page/Page column 55-56 ;

10320-42-02-氯-5-硝基嘧啶+

123-54-6乙酰丙酮

1450-76-62'-羟基-5'-硝基苯乙酮+

88626-94-2

参考文献

Chemistry of Heterocyclic Compounds (New York, NY, United States), , p. 1109 - 1112
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 19, # 10 p. 1393 - 1397

110-91-8吗啉+

10320-42-02-氯-5-硝基嘧啶

65735-66-24-(5-硝基嘧啶-2-基)吗啉

参考文献

MEDICAL RESEARCH COUNCIL
Patent: WO2009/122180 A1, 2009 ;
Location in patent: Page/Page column 95-96 ;
WO 2009/122180 A1

10320-42-02-氯-5-硝基嘧啶+

123-54-6乙酰丙酮

1450-76-62'-羟基-5'-硝基苯乙酮+

88626-94-2

参考文献

Remennikov, G. Ya.; Kisilenko, A. A.; Cherkasov, V. M.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , p. 1109 - 1112
Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 10 p. 1393 - 1397

109-01-3N-甲基哌嗪+

10320-42-02-氯-5-硝基嘧啶

943749-60-82-(4-甲基-1-哌嗪)-5-硝基嘧啶

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2008/147831 A1, 2008 ;
Location in patent: Page/Page column 36 ;
WO 2008/147831 A1