4-乙酰氨基-2-甲基苯甲酸合成路线 （共 8 条）
反应条件
potassium permanganate
参考文献
Biochemical Journal, , vol. 73, p. 377
参考文献
Chem. Zentralbl., , vol. 83, # I p. 136
反应条件
1: aluminium chloride; carbon disulfide 2: hydrogen peroxide; alkali View Scheme
参考文献
Chem. Zentralbl., , vol. 83, # I p. 136
参考文献
Bulletin de la Societe Scientifique de Bretagne, , vol. 31, p. Sonderheft S.9,41
Biochemical Journal, , vol. 73, p. 377
参考文献
Archiv der Pharmazie (Weinheim, Germany), , vol. 264, p. 447
Chem. Zentralbl., , vol. 83, # I p. 136
反应条件
1: With sulfuric acid 3 h; Heating / reflux; 2: With sodium hydroxide in water T=0°C; Alkaline aqueous solution;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2006/89909 A1, 2006 ;
Location in patent: Page/Page column 99 ;
参考文献
Richter
Archiv der Pharmazie (Weinheim, Germany), 1926 , vol. 264, p. 447
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Kunckell
Chem. Zentralbl., 1912 , vol. 83, # I p. 136
反应条件
1: With borane-THF in tetrahydrofuran T=20°C; 0.25 h; 2: With water in tetrahydrofuran
参考文献
GLAXO GROUP LIMITED
Patent: WO2009/68552 A1, 2009 ;
Location in patent: Page/Page column 25 ;
WO 2009/068552 A1
