1-(4-(4,4,5,5-四甲基-1,3,2-二氧硼戊环-2-基)苯基)环丁基氨基甲酸叔丁酯合成路线 （共 6 条）
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate in tetrahydrofuran 5 h; Reflux;
参考文献
WO2013/104611 A1, ;
Page/Page column 48 ;
反应条件
potassium acetate; Pd[P(t-Bu3)]2 in 1,4-dioxane T=80°C; 46 h;
参考文献
US2008/161317 A1, ;
Page/Page column 71-72 ;
反应条件
1.1: sodium hydrogencarbonate / dichloromethane; water 1.2: 20 °C / Inert atmosphere 2.1: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / tetrahydrofuran / 3 h / Reflux View Scheme
参考文献
WO2012/7345 A2, ;
WO 2012/007345 A2
反应条件
1.1: sodium hydrogencarbonate / dichloromethane; water 1.2: 20 °C / Inert atmosphere 2.1: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / tetrahydrofuran / 3 h / Reflux View Scheme
参考文献
WO2012/7345 A2, ;
WO 2012/007345 A2
反应条件
1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C / Inert atmosphere 2: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / tetrahydrofuran / Reflux View Scheme
参考文献
WO2012/7416 A1, ;
WO 2012/007416 A1
反应条件
1: tetrabutylammomium bromide; potassium hydroxide / water; toluene / 3 h / 70 - 100 °C 2: sodium hydroxide; water / butan-1-ol / 14 h / 120 °C 3: tetrabutylammomium bromide; sodium azide; zinc trifluoromethanesulfonate / tetrahydrofuran / 14 h / |Reflux 4: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct / N,N-dimethyl-formamide / 10 h / 80 °C / |Inert atmosphere View Scheme
