反应条件
1: ethyl (1-methyl-2-benzimidazolyl)acetate With lithium hexamethyldisilazane in tetrahydrofuran T=-78°C; 1 h; Inert atmosphere; 2: 1-methyl-2H-3,1-benzoxazine-2,4(1H)-dione in tetrahydrofuran T=-78 - 20°C; Inert atmosphere;
参考文献
Renhowe, Paul A.; Pecchi, Sabina; Shafer, Cynthia M.; Machajewski, Timothy D.; Jazan, Elisa M.; Taylor, Clarke; Antonios-McCrea, William; McBride, Christopher M.; Frazier, Kelly; Wiesmann, Marion; Lapointe, Gena R.; Feucht, Paul H.; Warne, Robert L.; Heise, Carla C.; Menezes, Daniel; Aardalen, Kimberly; Ye, Helen; He, Molly; Le, Vincent; Vora, Jayesh; Jansen, Johanna M.; Wernette-Hammond, Mary Ellen; Harris, Alex L.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 2 p. 278 - 292
