2-(4-氯-3-甲基-2-吡啶基甲硫基)-1H-苯并咪唑合成路线 （共 7 条）
反应条件
sodium hydroxide in water T=25°C; 4 h;
参考文献
Pharmazie, , vol. 60, # 11 p. 814 - 818
反应条件
1: 75 percent / phosphorus oxychloride / CH2Cl2 / 20 °C 2: 52 percent / CH2Cl2 / 12 h / Heating 3: 69 percent / triethylamine / acetonitrile / 18 h / 20 °C View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 43, # 6 p. 1447 - 1453
反应条件
1: 52 percent / CH2Cl2 / 12 h / Heating 2: 69 percent / triethylamine / acetonitrile / 18 h / 20 °C View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 43, # 6 p. 1447 - 1453
反应条件
1: 80 percent / SOCl2 / CH2Cl2 / 2 h / 25 °C 2: 94 percent / NaOH / H2O / 4 h / 25 °C View Scheme
参考文献
Pharmazie, , vol. 60, # 11 p. 814 - 818
反应条件
1: NaOH / H2O / 1 h / 25 °C 2: 80 percent / SOCl2 / CH2Cl2 / 2 h / 25 °C 3: 94 percent / NaOH / H2O / 4 h / 25 °C View Scheme
参考文献
Pharmazie, , vol. 60, # 11 p. 814 - 818
反应条件
potassium hydroxide in dimethyl sulfoxide T=20°C; 336 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 43, # 6 p. 1447 - 1453
反应条件
1: 29.5 percent / potassium hydroxide / dimethylsulfoxide / 336 h / 20 °C 2: 33.5 percent / aq. sodium carbonate; peracetic acid / CH2Cl2 / 20 h / 20 °C View Scheme
参考文献
Radl, Stanislav; Klecan, Ondrej; Havlicek, Jaroslav
Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 6 p. 1447 - 1453
