sodium hydrogencarbonate Yield given;

phosphorus pentachloride 1.) 20 min, 160 deg C, 2.) 30 min, 100 deg C; Yields of byproduct given;

1: 56 percent / PCl5 / 1.) 20 min, 160 deg C, 2.) 30 min, 100 deg C 2: 93 percent / 2 - 3 weeks, RT View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605283', constants.ctx, '0')">triethylamine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '635760', constants.ctx, '0')">toluene</a> <br />T=80&deg;C;&nbsp;1&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 91 percent / SOCl₂ / dimethylformamide / 26 h / Ambient temperature<br />2: 66 percent / triethylamine / CH₂Cl₂; various solvent(s); petroleum ether / 14 h / 70 &deg;C<br />3: 99 percent / 1 h / 50 - 60 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 66 percent / triethylamine / CH₂Cl₂; various solvent(s); petroleum ether / 14 h / 70 &deg;C<br />2: 99 percent / 1 h / 50 - 60 &deg;C<br /> <br /> &nbsp;