甲基(2S)-1-(氯甲酰基)-2,3-二氢-1H-吡咯-2-羧酸酯合成路线 （共 3 条）
反应条件
1: 91 percent / SOCl2 / dimethylformamide / 26 h / Ambient temperature 2: 2.) H2, Pd/CE 10R / 1.) CH2Cl2, 15-25 deg C, 3 h, 2.) ethyl acetate, 60 deg C, from 200 to 100 bar, 96 h View Scheme
参考文献
Drauz, Karlheinz; Kleemann, Axel; Martens, Juergen; Scherberich, Paul; Effenberger, Franz
Journal of Organic Chemistry, 1986 , vol. 51, # 18 p. 3494 - 3498
反应条件
hydrogen; palladium 1.) CH2Cl2, 15-25 deg C, 3 h, 2.) ethyl acetate, 60 deg C, from 200 to 100 bar, 96 h; Yield given. Multistep reaction;
参考文献
Drauz, Karlheinz; Kleemann, Axel; Martens, Juergen; Scherberich, Paul; Effenberger, Franz
Journal of Organic Chemistry, 1986 , vol. 51, # 18 p. 3494 - 3498
反应条件
1: H2, Pd/CE 10R / dioxane / 30 h / 40 °C / 75005.9 Torr 2: 97 percent / aq. HCl / 25 - 75 °C View Scheme
参考文献
Drauz, Karlheinz; Kleemann, Axel; Martens, Juergen; Scherberich, Paul; Effenberger, Franz
Journal of Organic Chemistry, 1986 , vol. 51, # 18 p. 3494 - 3498
