N-2-硝基苯基-2,6-二氟苯胺合成路线 （共 2 条）
反应条件
1: 2,6-Difluoroaniline With NaOtAm in tetrahydrofuran T=0 - 10°C; 1.11667 h; Large scale reaction; 2: 2-fluoro-1-nitrobenzene in tetrahydrofuran T=9 - 15°C; 3 h; Large scale reaction; Thermodynamic data; ConcentrationTime;
参考文献
Connolly, Terrence J.; Auguscinski, Waldemar; Fung, Peter; Galante, Rocco; Liu, Weiguo; McGovern, Linda; Sebastian, Alice; Shen, Xiaole; Shi, Xinxu; Wilk, Boguslawa; Varsalona, Richard; Zhong, Huijuan
Organic Process Research and Development, 2010 , vol. 14, # 4 p. 868 - 877
反应条件
hydrogen; nickel in ethanol P=2068.65 Torr; 1 h;
参考文献
WYETH
Patent: WO2008/73459 A1, 2008 ;
Location in patent: Page/Page column 136 ;
WO 2008/073459 A1
