N-(2,6-二氟苯基)-1,2-苯二胺合成路线 （共 2 条）
反应条件
hydrogen; nickel in ethanol P=2068.65 Torr; 1 h;
参考文献
WYETH
Patent: WO2008/73459 A1, 2008 ;
Location in patent: Page/Page column 136 ;
WO 2008/073459 A1
反应条件
1.1: NaOtAm / tetrahydrofuran / 1.12 h / 0 - 10 °C / Large scale reaction 1.2: 3 h / 9 - 15 °C / Large scale reaction 2.1: palladium 10 on activated carbon; hydrogen / tetrahydrofuran / 2 h / 45 °C / 3087.28 - 3604.44 Torr / Large scale reaction View Scheme
参考文献
Connolly, Terrence J.; Auguscinski, Waldemar; Fung, Peter; Galante, Rocco; Liu, Weiguo; McGovern, Linda; Sebastian, Alice; Shen, Xiaole; Shi, Xinxu; Wilk, Boguslawa; Varsalona, Richard; Zhong, Huijuan
Organic Process Research and Development, 2010 , vol. 14, # 4 p. 868 - 877
