1-(溴甲基)-2-异丙基苯合成路线 （共 2 条）
反应条件
phosphorus tribromide in diethyl ether T=20°C;
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/66144 A1, 2005 ;
Location in patent: Page/Page column 40-41 ;
WO 2005/066144 A1
反应条件
1: n-BuLi / tetrahydrofuran; hexane / 160 °C 2: PBr3 / diethyl ether / 20 °C View Scheme
参考文献
Zhi, Lin; Tegley, Christopher M.; Pio, Barbara; Edwards, James P.; Motamedi, Mehrnouch; Jones, Todd K.; Marschke, Keith B.; Mais, Dale E.; Risek, Boris; Schrader, William T.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 19 p. 4104 - 4112
