2-(1-吡咯基)苯甲酸甲基酯合成路线 （共 12 条）
反应条件
acetic acid in 1,4-dioxane 2 h; Reflux;
参考文献
Cadogan; Clark, Bernard A. J.; Ford, Daniel; MacDonald, Ranald J.; MacPherson, Andrew D.; McNab, Hamish; Nicolson, Iain S.; Reed, David; Sommerville, Craig C.
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 24 p. 5173 - 5183
反应条件
in 1,4-dioxane; water
参考文献
Adir et Compagnie
Patent: US5627203 A1, 1997 ;
反应条件
sodium tetrahydroborate; sulfuric acid; water in tetrahydrofuran; methanol T=10 - 20°C; 1.5 h; Yield given;
参考文献
Verardo, Giancarlo; Dolce, Anna; Toniutti, Nicoletta
Synthesis, 1999 , # 1 p. 74 - 79
反应条件
in acetic acid; acetone
反应条件
potassium carbonate in N,N-dimethyl-formamide Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 2 p. 596 - 604
反应条件
n-butyllithium; N,N,N',N,-tetramethylethylenediamine in diethyl ether; hexane T=0°C; 32 h;
参考文献
Tetrahedron, , vol. 49, # 45 p. 10271 - 10278
反应条件
1: LAH / diethyl ether / 0 °C 2: PCC / CH2Cl2 / 20 °C View Scheme
参考文献
Li, Zhenghua; Kumar, Amit; Vachhani, Dipak D.; Sharma, Sunil K.; Parmar, Virinder S.; Van Der Eycken, Erik V.
European Journal of Organic Chemistry, 2014 , vol. 2014, # 10 p. 2084 - 2091
反应条件
hydrazine hydrate in ethanol 3 h;
参考文献
Artico, Marino; Corelli, Federico; Massa, Silvio; Stefancich, Giorgio; Avigliano, Luciana; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 4 p. 802 - 806
反应条件
lithium aluminium tetrahydride in diethyl ether 0.25 h;
参考文献
Li, Zhenghua; Kumar, Amit; Vachhani, Dipak D.; Sharma, Sunil K.; Parmar, Virinder S.; Van Der Eycken, Erik V.
European Journal of Organic Chemistry, 2014 , vol. 2014, # 10 p. 2084 - 2091
参考文献
Bailey, A. Sydney; Scott, Peter W.; Vandrevala, Marazban H.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 97 - 101
