S-Boc-β-苯丙氨酸合成路线 （共 30 条）
反应条件
sodium hydroxide in 1,4-dioxane; water T=0 - 20°C; 3.5 h;
参考文献
WO2004/20432 A1, ;
Page/Page column 57 ;
反应条件
lithium hydroxide in tetrahydrofuran; methanol T=0 - 20°C; 1 h;
参考文献
Synlett, , # 12 p. 2039 - 2040
反应条件
1: 99 percent / (R)-N-3,5-(CF3Ph)2-thiourea-6'-MeO-chinchona alkaloid / acetone / 36 h / -60 °C 2: H2 / Pd/C / methanol / 10 h / 20 °C 3: toluene / 2 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 128, # 18 p. 6048 - 6049
反应条件
1: H2 / Pd/C / methanol / 10 h / 20 °C 2: toluene / 2 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 128, # 18 p. 6048 - 6049
反应条件
potassium permanganate; sodium periodate in water 16 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 56, # 20 p. 5883 - 5889
反应条件
ruthenium trichloride; sodium periodate in tetrachloromethane; water; acetonitrile
参考文献
Tetrahedron Letters, , vol. 48, # 40 p. 7094 - 7098
反应条件
sodium hydroxide in ethanol T=90°C; 3 h; Yield given;
参考文献
Tetrahedron Letters, , vol. 30, # 34 p. 4539 - 4542
反应条件
ruthenium trichloride; sodium periodate in tetrachloromethane; water; acetonitrile 2.5 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 56, # 20 p. 5883 - 5889
反应条件
1: With lithium hydroxide in tetrahydrofuran T=0 - 20°C; 6 h; 2: in toluene 2.5 h; Heating; Further stages.;
参考文献
Chemistry - A European Journal, , vol. 13, # 29 p. 8338 - 8351
反应条件
1: Na2CO3, Et3N / methanol / 1 h / 65 °C 2: CCl4, PPh3 / 4 h / 80 °C 3: 1.) n-BuLi, LiC10H7 / 1.) THF, hexane, -78 deg C, 3 h, 2.) THF, hexane, from -78 to 20 deg C, overnight View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 7, # 10 p. 2911 - 2922
