4-苯基-1,2,3,6-四氢吡啶合成路线 （共 22 条）
反应条件
1: HCl 2: NaOH View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 22 p. 3951 - 3954
反应条件
hydrogenchloride T=80°C; 24 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 23 p. 7106 - 7109
反应条件
sodium hydroxide in water
参考文献
WO2004/113275 A2, ;
Page 171 ;
反应条件
formaldehyd; ammonium chloride 2-taegiges Behandeln mit Me. u. Erw. mit konz. wss. Salzsaeure;
参考文献
Journal of the American Chemical Society, , vol. 78, p. 1702,1704
Journal of Medicinal and Pharmaceutical Chemistry, , vol. 1, p. 281,284
参考文献
Journal of the American Chemical Society, , vol. 78, p. 1702,1704
反应条件
1: HCl; AcOH 2: HCl 3: NaOH View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 22 p. 3951 - 3954
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C 1.2: 2 h / 20 °C 1.3: 15 h / -78 - 20 °C 2.1: trifluoroacetic acid / dichloromethane / 5 h / 0 - 20 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 74, p. 246 - 257
反应条件
male Wistar rat liver microsomes; NADPH-generating system in phosphate buffer T=37°C; oxidative N-demethylation; pH=7.4; 0.25 h; Enzyme kinetics;
参考文献
Chemical Research in Toxicology, , vol. 9, # 1 p. 93 - 98
反应条件
1: Pd(OAc)2 2: HCl 3: NaOH View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 22 p. 3951 - 3954
反应条件
1: HCl; AcOH 2: HCl 3: NaOH View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 22 p. 3951 - 3954
