1: water; potassium hydroxide / methanol / 24 h / Reflux 2: bromine / water / 2 h / 0 - 5 °C View Scheme

1: water; potassium hydroxide / methanol / 24 h / Reflux 2: ethanol; water / 1 h / 20 °C 3: acetic acid / 2 - 4 h / 100 °C 4: sodium tetrahydroborate / dichloromethane; water; isopropyl alcohol / 16 h / 20 - 25 °C View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1: sulfuric acid / acetic acid / 1 h / 100 &deg;C<br />2: sodium hypochlorite; sodium hydroxide / methanol / 24 h / 25 &deg;C<br />3: hydrogen / methanol / 20 h / 80 &deg;C / 22502.3 Torr<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: sodium hypochlorite; sodium hydroxide / methanol / 24 h / 25 &deg;C<br />2: hydrogen / methanol / 20 h / 80 &deg;C / 22502.3 Torr<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587189', constants.ctx, '0')">hydrogen</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '10050758', constants.ctx, '0')">DiPh-MeO-Biphep</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '17903402', constants.ctx, '0')">bis(norbornadiene)rhodium(I) hexafluorophosphate</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />T=60&deg;C;&nbsp;P=3750.38&nbsp;Torr;&nbsp;20&nbsp;h;&nbsp;&nbsp;Product distribution / selectivity;&nbsp;<br /> <br /> &nbsp;