2-碘-5-甲基苯甲酸甲酯合成路线 (共 13 条)
反应条件
1: dppf / Pd2(dba)3 / dimethylformamide / 120 °C 2: NBS; benzoyl peroxide / CCl4 / Heating View Scheme
参考文献
Pharmacia Corporation
Patent: US6664255 B1, 2003 ;
US 6664255 B1
反应条件
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / toluene; ethanol / 24 h / |Reflux
2: sodium hydroxide; water / methanol / 2 h / 65 °C
View Scheme
参考文献
Wang, Yang; Gulevich, Anton V.; Gevorgyan, Vladimir
Chemistry - A European Journal, 2013 , vol. 19, # 47 p. 15836 - 15840
反应条件
1: Cu / dimethylformamide
2: NaOH, EtOH
View Scheme
参考文献
Carruthers,W.; Pooranamoorthy,R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1974 , p. 2405 - 2409