(S)-3-(Cbz-氨基)-2-氧代氮杂烷合成路线 （共 4 条）
反应条件
sodium hydrogencarbonate in tetrahydrofuran; water T=20°C; 18 h;
参考文献
Abe, Masatoshi; Akiyama, Tetsuo; Umezawa, Yoji; Yamamoto, Keiichiro; Nagai, Masashi; Yamazaki, Hiroko; Ichikawa, Yuh-Ichiro; Muraoka, Yasuhiko
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 3 p. 785 - 797
反应条件
1: 95 percent / N3Tf; CuSO4; K2CO3 / CH2Cl2; methanol; H2O 2: 97 percent / N,N'-dicyclohexylcarbodiimide / CH2Cl2 / 0 °C 3: 80 percent / 1,4-diazabicyclo[2.2.2]octane / tetrahydrofuran; H2O / 70 °C View Scheme
参考文献
David, Olivier; Meester, Wim J. N.; Bieraeugel, Hans; Schoemaker, Hans E.; Hiemstra, Henk; Van Maarseveen, Jan H.
Angewandte Chemie - International Edition, 2003 , vol. 42, # 36 p. 4373 - 4375
反应条件
sodium hydrogencarbonate in tetrahydrofuran; water T=0 - 20°C; 18 h;
参考文献
ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI
Patent: EP1184388 A1, 2002 ;
Location in patent: Example 7 ;
参考文献
Brenner; Rickenbacher
Helvetica Chimica Acta, 1958 , vol. 41, p. 181,186
