triethylsilane; aluminium trichloride in chloroform T=20°C;

trifluoroacetic acid in dichloromethane; toluene T=20°C; 1 h;

1: N-methyl-N-nosyl-L-valine phenacyl ester With benzenethiol sodium salt in N,N-dimethyl-formamide T=20°C; 3 h; Inert atmosphere; 2: With sodium carbonate in water pH=9; 3: (9H-Fluoren-9-yl)-methyl chloroformate in 1,4-dioxane T=0°C;

1: toluene-4-sulfonic acid / toluene / 2 h / |Reflux 2: triethylsilane; trifluoroacetic acid / acetonitrile / 2 h / 75 °C / |Flow reactor View Scheme

Multistep reaction.;

Yield given. Multistep reaction;