4-(4-叠氮基苯基)丁酸合成路线 (共 2 条)
反应条件
1: With sulfuric acid; sodium nitrite T=0°C; Diazotization; 0.75 h; 2: With sodium azide T=0°C; Substitution; 0.666667 h;
参考文献
Halmos, Therese; Turek, Joseph W.; Le Breton, Guy C.; Antonakis, Kostas
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 20 p. 2963 - 2968
反应条件
1.1: 85 percent / H2 / 10 percent Pd/C / methanol / 6 h / 20 °C 2.1: aq. NaNO2; aq. H2SO4 / 0.75 h / 0 °C 2.2: 71 percent / aq. NaN3 / 0.67 h / 0 °C View Scheme
参考文献
Halmos, Therese; Turek, Joseph W.; Le Breton, Guy C.; Antonakis, Kostas
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 20 p. 2963 - 2968