反应条件
1: H2, NH3, Raney nickel / ethanol / 2 h / 50 °C / 3040 - 3800 Torr
2: conc. H2SO4 / 1 h / Ambient temperature
3: 71 percent / diethyl ether; 1,2-dichloro-ethane / 1 h
View Scheme
参考文献
Cliffe, Ian A.; Lien, Eric L.; Mansell, Howard L.; Steiner, Kurt E.; Todd, Richard S.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 7 p. 1169 - 1175
