2-[(三甲基甲硅烷基)乙炔基]苯胺合成路线 （共 40 条）
反应条件
methanol; potassium fluoride T=20°C;
参考文献
Li, Zhen; Hong, Longcheng; Liu, Ruiting; Shen, Jianzhong; Zhou, Xigeng
Tetrahedron Letters, 2011 , vol. 52, # 12 p. 1343 - 1347
反应条件
1: 92 percent / TBAF / tetrahydrofuran / 0.5 h / 20 °C 2: 81 percent / CuI; Et3N; PdCl2(PPh3)2 / tetrahydrofuran / 3 h / 20 °C 3: 82 percent / KH / 1-methyl-pyrrolidin-2-one / 3 h / 20 °C View Scheme
参考文献
Koradin, Christopher; Dohle, Wolfgang; Rodriguez, Alain L.; Schmid, Bertram; Knochel, Paul
Tetrahedron, 2003 , vol. 59, # 9 p. 1571 - 1587
反应条件
1.1: NaNO2; 6N HCl / H2O / 0.5 h / 0 °C 1.2: 73 percent / 3 h / Heating 2.1: 77 percent / POCl3 / pyridine; chlorobenzene / 1 h / Heating View Scheme
参考文献
Gautheron Chapoulaud; Ple; Turck; Queguiner
Tetrahedron, 2000 , vol. 56, # 30 p. 5499 - 5507
反应条件
1,2,2-trichloro-1,1,2-trichloro-ethane; triethylamine in benzene T=20°C; 4 h;
参考文献
Saito, Takao; Nihei, Hiroshi; Otani, Takashi; Suyama, Toshiyuki; Furukawa, Naoki; Saito, Masatoshi
Chemical Communications, 2008 , # 2 p. 172 - 174
参考文献
Shi; Wang
Journal of Organic Chemistry, 1998 , vol. 63, # 10 p. 3517 - 3520
反应条件
1: tetrahydrofuran / 12 h / 0 °C 2: 2.28 g / triethylamine; phosphorous oxychloride / tetrahydrofuran / 2 h / 0 °C 3: 86 percent / potassium carbonate / 6 h / 20 °C 4: 76 percent / dichlorobis(triphenylphosphine)nickel(II) / diethyl ether / 96 h / Heating View Scheme
参考文献
Organic Letters, , vol. 1, # 12 p. 1977 - 1979
反应条件
1: 0.940 g / KF/Al2O3 / 0.07 h / microwave irradiation (30 percent power) 2: 88 percent / Et3N / tetrahydrofuran / -15 - 20 °C 3: PPh3; CuI; Pd / KF/Al2O3 / microwave irradiation View Scheme
参考文献
Kabalka, George W.; Wang, Lei; Pagni, Richard M.
Tetrahedron, 2001 , vol. 57, # 38 p. 8017 - 8028
反应条件
1: With hydrogenchloride; sodium nitrite in water T=0°C; Diazotization; 0.5 h; 2: Cyclization; 3 h; Heating;
参考文献
Gautheron Chapoulaud; Ple; Turck; Queguiner
Tetrahedron, 2000 , vol. 56, # 30 p. 5499 - 5507
反应条件
1: TBAF / tetrahydrofuran / 0 - 20 °C 2: 61 percent / acetonitrile / 12 h / 150 °C View Scheme
参考文献
Lee, Jae Hak; Lee, Byoung Se; Shin, Hyunik; Nam, Do Hyun; Chi, Dae Yoon
Synlett, 2006 , # 1 art. no. U27905ST, p. 65 - 68
反应条件
1: 70 percent / 1,1'-bis(diphenylphosphino)ferrocene, Bu4NF, Et3N / PdCl2 / tetrahydrofuran / Ambient temperature 2: 67 percent / HCOONH4 / 10 percent Pd/C / methanol / 1 h / 70 °C View Scheme
参考文献
Cacchi, Sandro; Fabrizi, Giancarlo; Marinelli, Fabio
Synlett, 1999 , # 4 p. 401 - 404
