1: 1-bromo-4-methoxy-benzene With (nBu)3MgLi in tetrahydrofuran
T=0°C; 0.0833333 h;
2: 1-trifluoromethyl-4-bromobenzene With Cl2Ni(1,2-bis(diphenylphosphino)ethane) in tetrahydrofuran
T=0°C; Kumada-Corriu cross-coupling; Further stages.;
参考文献
Lau, Stephen Y. W.; Hughes, Greg; O'Shea, Paul D.; Davies, Ian W.
Organic Letters, 2007 , vol. 9, # 11 p. 2239 - 2242
1: triallyl(4-methoxyphenyl)silane With tetrabutyl ammonium fluoride in tetrahydrofuran; water
T=20°C; 1 h;
2: 1-chloro-4-(trifluoromethyl)benzene With 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl; bis(η3-allyl-μ-chloropalladium(II)) in tetrahydrofuran; water
T=80°C; 3 h;
Pd0(tris(tert-butyl)phosphine)2; biphenyl in toluene
T=90°C; 20 h; Inert atmosphere;
参考文献
Denmark, Scott E.; Smith, Russell C.; Chang, Wen-Tau T.; Muhuhi, Joseck M.
Journal of the American Chemical Society, 2009 , vol. 131, # 8 p. 3104 - 3118
