2,2-二甲基-5-辛酰-1,3-二恶烷-4,6-二酮合成路线 （共 6 条）
反应条件
pyridine in dichloromethane 1 h; Ambient temperature;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 55, # 7 p. 2186 - 2189
参考文献
Lokot, Igor P.; Pashkovsky, Felix S.; Lakhvich, Fedor A.
Tetrahedron, 1999 , vol. 55, # 15 p. 4783 - 4792
反应条件
in methanol 5 h; Heating; Yield given;
参考文献
Nakahata, Masaaki; Imaida, Motomasa; Ozaki, Hiroshi; Harada, Tadao; Tai, Akira
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 7 p. 2186 - 2189
参考文献
The University of Tokyo; Otsuka Chemical Co., Ltd.
Patent: EP2221293 A1, 2010 ;
Location in patent: Page/Page column 10 ;
反应条件
1: 94 percent / 2 h / Heating
2: 1.) NaOMe, 2.) 1N HCl / 1.) MeOH, H2O, 8 h
3: 98 percent / Et3N, DMAP, DCC / CH2Cl2 / 6 h / Ambient temperature
4: 97 percent / toluene / Heating
View Scheme
参考文献
Lokot, Igor P.; Pashkovsky, Felix S.; Lakhvich, Fedor A.
Tetrahedron, 1999 , vol. 55, # 15 p. 4783 - 4792
反应条件
1: 16 h / Heating
2: 82 percent / H2, HCl / Ru<(R)BINAP>2 / methanol / 48 h / 40 °C / 10343 Torr
View Scheme
参考文献
Kocienski, Philip J.; Pelotier, Beatrice; Pons, Jean-Marc; Prideaux, Heather
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 8 p. 1373 - 1382
