1: 1.70 g / DMAP; Et3N / CH2Cl2 / 20 °C 2: 75 percent / iodine / acetonitrile / 16 h / 0 - 20 °C 3: 81 percent / DBU / dimethylformamide / 1 h / 90 °C View Scheme

Multi-step reaction with 3 steps 1: 78 percent / pyridine / CH2Cl2 / 3 h / 0 - 20 °C2: 63 percent / 1,2-bis(diphenylphosphino)ethane / tetrakis(triphenylphosphine)palladium(0) / tetrahydrofuran / 24 h / 20 °C3: 52 percent / aq. HCl / diethyl ether / 1 h